REMEDIUM

The article substantiates the need for a systematic approach to organizing nutritional support for cardiac surgery patients. The high prevalence of protein—energy deficiency among this patient population is noted, as well as its impact on treatment outcomes and postoperative rehabilitation. The reasons for the underestimation of nutritional therapy in clinical practice are analyzed, and organizational measures aimed at standardizing the processes of assessment, prescription, and monitoring of nutrition are described. The development of such a project is considered an important step toward optimizing the quality of medical care and ensuring the rational use of hospital resources.

This article explores the potential of telemedicine technologies in optimizing the care of elderly patients. Based on semi-structured interviews with experts, key factors were identified that determine the successful adaptation of telemedicine to the needs of this age group. The analysis of expert assessments revealed the challenges that hinder adaptation and provided recommendations for the development and implementation of telemedicine solutions that take into account the specific needs of the elderly. The results of this study can be used to improve the accessibility and quality of healthcare for the elderly.

The aim of the study was to examine the current state and prospects of development of production pharmacies in Russia, as well as their readiness for the manufacture of cardioplegic solutions according to a specific prescription for providing cardiac surgery. The analysis of the Roszdravnadzor license registry data and a survey of institutions in the Central Federal District revealed that only a few number of pharmacies have the necessary conditions and resources for aseptic production. Major barriers include lack of components, equipment, qualified personnel and regulatory constraints. The need for regulatory changes and the introduction of modern manufacturing standards, including the use of international experience in compounding, and quality control in the activities of pharmacies with prescription and production departments to improve the availability of drugs in cardiac surgery is noted. The availability of drugs for cardiac surgery can be improved by implementing regulatory changes and modern manufacturing standards, including international compounding experience and quality control in the activities of pharmacies with prescription and production departments.

Introduction. The modern lifestyle of girls, including behavioral patterns, social practices and value orientations, has a significant impact on their physical and psycho-emotional well-being. With the increasing prevalence of unhealthy habits in this group, the study of the relationship between lifestyle and subjective assessment of health is becoming particularly relevant. Objective. To identify patterns of association between behavioral lifestyle factors (physical activity, nutrition, smoking, alcohol consumption) and subjective health assessment among youth. Methods. A cross-sectional online survey was conducted among 214 females aged 18—22 years (Me [Q1; Q3] = 20 [19; 21]) using a combined questionnaire that included sections on self-rated health, physical activity, dietary habits, and harmful behaviors. Statistical analysis involved calculation of relative measures, Pearson's χ² test, and correlation analysis. Results. Age-related dynamics were revealed: positive health assessments decreased with age (r = −0.23). Regular physical activity was associated with higher self-rated health (r = 0.45). Balanced nutrition correlated with improved subjective assessment (r = 0.38), while smoking (r = −0.52) and alcohol consumption (r = −0.39) showed inverse relationships. Conclusion. The results confirm the significant influence of a healthy lifestyle on the subjective perception of health in girls. The formation of programs aimed at increasing physical activity, rationalizing nutrition and giving up bad habits can help improve both objective and subjective health in this group.

The article considers dentophobia as a significant biopsychosocial phenomenon that affects the quality of life and the structure of dental care. It is shown that the fear of dental intervention is formed under the influence of personal negative experiences, social learning, cultural beliefs and informational influences, which leads to a steady avoidance of preventive visits and late treatment. An analysis of these studies demonstrates that severe dental anxiety is associated with a deterioration in dental status, a decrease in psychological well-being, and an increased need for complex invasive interventions. The conclusion is drawn about the need for a comprehensive interdisciplinary approach, including improving communication, improving medical literacy and developing patient-oriented care strategies.

In the context of strict regulatory requirements and the desire for continuous improvement, pharmaceutical companies are faced with the need to improve the efficiency and reliability of their quality management systems (QMS). Traditional approaches to the audit of QMS documentation, based on manual analysis, are time-consuming, subject to the human factor and do not always provide the necessary depth of analysis FarBrain, which uses artificial intelligence (AI) technologies for automated audit of QMS documents. The system is designed to analyze various types of documents, including standard operating procedures (SOPs), corrective and preventive action plans (CAPAs), quality policies and reports, for compliance with a wide range of international and national standards, such as EAEU GMP, ICH Q10, ISO 9001, PIC/S Guide, GAMP 5 and FDA 21 CFR Part 11. The system is based on natural language processing (NLP) and machine learning (ML) algorithms that automatically extract key information, identify inconsistencies and potential risks, and make recommendations for improvement. The article describes in detail the methods behind the operation of the system, including the architecture, the AI algorithms used, and the validation process in accordance with the principles of GMP. In addition, the results demonstrating the functionality of the system are presented and compared with other existing AI solutions in the field of quality management. The advantages, challenges and prospects of introducing AI into QMS audit processes are discussed, emphasizing the importance of integration with other digital systems and the development of predictive analytics to ensure a high level of quality and safety of pharmaceutical products.

The article is devoted to the improvement of the conceptual apparatus of state control (supervision) in the field of health protection in terms of preventive measures. The article examines the structural features of the term «prevention» provided for in various areas of legislation, and also studies the specifics of preventive measures provided for by the provisions on state control (supervision) in the field of circulation of medicines, as well as the quality and safety of medical activities. Definitions for various types of preventive measures have been developed and proposed, aspects have been identified in relation to which legislative improvement is potentially possible. The application of the above proposals will ensure a uniform interpretation and application of various preventive measures, as well as take into account the specifics of the healthcare sector, including centuries-old experience in risk management.

The article examines the organizational and managerial conditions that ensure the development and successful implementation of corporate employee wellness programs. Based on the analysis of international and Russian experience, key socio-economic and organizational factors determining the effectiveness of these initiatives in commercial companies have been identified. The author's classification of corporate healthy lifestyle programs by goals, forms of implementation, target groups of employees and levels of integration into the management system of the organization has been formed. The necessity of integrating wellness programs into the human resource management strategy and corporate social responsibility as a condition for productivity growth, staff retention and the formation of a sustainable employer brand is substantiated.

The article presents the materials of the last major outbreak of diphtheria in the Russian Federation at the end of the 20th century (1990—1997), in the measures to eliminate which employees of the Department of Infectious Diseases and Epidemiology of the Russian University of Medicine of the Ministry of Health of Russia (former Moscow Medical Dental Institute) participated.