REMEDIUM

This article examines organizational technologies aimed at reducing anxiety in elderly patients in a dental clinic. Dental fear (dentophobia) in older patients is a common problem affecting the quality of dental care and overall health. The author analyzes psychological and organizational approaches, including environmental adaptations, communication strategies, and the use of additional relaxation techniques. A study involving 120 patients aged 60+ years identified key factors influencing fear levels and treatment satisfaction. The results demonstrate a significant reduction in anxiety with the implementation of the proposed technologies.

The study is devoted to the development of the medical industry in Russia. By studying best global practices, we can identify promising areas for public administration development and substantiate support measures. The purpose of the study is to analyze international management and regulatory experience in the medical equipment industry and identify factors for the industry's promising development, with the goal of adopting successful management practices from other countries for the Russian economy. Materials and Methods. The research methodology utilizes statistical methods of data analysis, comparative analysis, and a systems approach to analyzing the medical industry. Results. The article highlights factors for the industry's successful development and proposes an algorithm for developing the Russian medical industry and measures for public administration based on international experience. Conclusion. International experience in medical industry development demonstrates the availability of a set of proven tools that, if properly adapted, can accelerate the growth of the domestic industry. These tools include long-term investment in innovation, cluster formation and cooperation, export promotion, implementation of the best technological solutions, a well-thought-out regulatory policy, and reliance on human capital.

The pharmaceutical industry is a vital economic sector, ensuring public health and national security. In the face of global sanctions, a shortage of active pharmaceutical ingredients (APIs), and growing demand for innovative medicines, Russia faces the need for accelerated import substitution and technological sovereignty. This article analyzes current trends in the development of the pharmaceutical industry in the Russian Federation: from structural shifts in production to the introduction of digital technologies, regulatory changes, and the formation of local supply chains. The author identifies the factors that determine the sustainable development of the pharmaceutical industry. Particular attention is paid to the role of government support, including import substitution programs, tax incentives, modernization of production facilities, and the development of research potential. The analysis shows that, despite significant advances in the production of generics and essential drugs, systemic risks persist: a shortage of high-tech substances, low investment in the industry, insufficient integration of pharmaceutical research and industry, and a fragmented regulatory environment.

This article examines the protection of foreign patients' personal data amid the rapidly expanding export of medical services in the Russian Federation. Using St. Petersburg as an example, a retrospective analysis of the dynamics of foreign citizens' requests for medical care from 2018 to 2024 was conducted, revealing a nearly threefold increase in their number. The country breakdown of patients was examined, revealing a predominance of citizens from the CIS and neighboring countries. Particular attention is paid to the analysis of Russian national legislation and international legal frameworks (GDPR, HIPAA, and PIPL) governing the processing and cross-border transfer of medical personal data. Key issues related to information security in medicine are identified, including the risks of leaks and the need to harmonize Russian and international regulations. Therefore, the need for a comprehensive approach combining improved legal frameworks for data protection with the development of organizational security mechanisms is substantiated, a key condition for the sustainable development of medical tourism.

Improving life expectancy and quality of life is a key priority of state social policy, enshrined in the strategic documents of the Russian Federation. In light of the new national goals formulated in Presidential Decree No. 309 dated 07.05.2024, comprehensive monitoring of demographic indicators becomes a tool for assessing the effectiveness of healthcare and socio-economic measures. The aim of the study was to conduct a retrospective comparative analysis of the dynamics of life expectancy at birth (LE), life expectancy at age 55 (LE-55), and healthy life expectancy (HALE) in the Russian Federation, the Volga Federal District, and the Samara Region for the periods from 1990 to 2024 to identify regional characteristics and trends. The work used data from the Federal State Statistics Service. The analysis of LE dynamics (1990—2023) was conducted with a breakdown by sex and type of settlement (urban/rural population). Indicators of LE-55 (2018—2023) and HALE (2019—2024) were examined. Statistical processing included linear regression analysis to estimate average annual rates of change, Student's t-test to test trend significance, one-way analysis of variance (ANOVA), and pairwise comparison methods to assess intergroup differences. It was established that in the Russian Federation for 1990—2023, a U-shaped LE trend was identified with an average annual increase of +0.18 years (p < 0.001). The gender gap remained at the level of 10—12 years, the urban-rural gap at 1.2—1.5 years. The dynamics in the Volga Federal District mirrored the all-Russian trend with a smaller amplitude of fluctuations. The Samara Region demonstrated a unique profile: a shallower decline in the 1990s, an earlier recovery, the smallest drop in LE during the COVID-19 pandemic (−0.4 years vs. −1.76 years in the RF), and the smallest urban-rural gap (0.69 years in 2023). However, the region recorded one of the highest gender gaps in the country (11.07 years in 2023). Analysis of LE-55 revealed a V-shaped trend related to the pandemic, with the Samara Region showing the smallest decline (-0.88 years) and the most pronounced recovery. The HALE indicator in the Samara Region grew at an average annual rate of +0.65 years (p = 0.03), which is the highest among the compared regions, reaching leading positions by 2023—2024 (63.4 years). Thus, the identified specific medico-demographic profile of the Samara Region is characterized by high resilience to crises and significant potential for improving the quality of life. However, to achieve national goals (78 years by 2030), the critical limiting factors remain the high level, structure, and causes of mortality, especially among the male population. The obtained data substantiate the need for an in-depth analysis of mortality as a key determinant of life expectancy for the development of targeted regional programs.

Introduction. Bulk powders provide reliable process operations for producing pharmaceuticals based on them, such as filling and unloading from bins, as well as filling capsules and tablet press dies. In pharmaceutical production, powdered materials are subject to a variety of significant technological processes, which can result in significant changes in the physical properties of the particles, affecting their flowability. To maintain consistent product quality and effectively manage bulk material processes, it is necessary to consider the mechanisms underlying flowability and the critical process parameters at each stage of production. Understanding the key characteristic — the flowability of powdered materials — at virtually all stages of production determines the effectiveness of fluidization, mixing, milling, granulation, and tableting processes. The aim of this study is to investigate the pharmaceutical and technological characteristics of the fractional composition and grindability of a 3,6,9-triazatricyclotetradecane derivative. Materials and Methods. Standardized pharmacopoeial methods were used as experimental research tools, allowing for the description of various aspects of powder flow properties. The obtained research results were statistically substantiated, ensuring the validity of the obtained results. Results. A 3,6,9-triazatricyclotetradecane derivative was shown to exhibit poor flowability, representing a powder fraction with a particle size range greater than 94 μm but less than 355 μm. According to the established data, the powder fraction consists primarily of particles in the size range from 180 μm to 94 μm, which characterizes it as a finely dispersed powder. Classic powder classification terms in accordance with OFS.1.4.2.0032 were deemed inapplicable, and fineness was defined as a percentage of the powder mass passing through a sieve of a given size. Based on the results of a natural angle of repose study, flowability was characterized as "very poor". The compressibility and Hausner coefficients ranged from 28 to 31 and 1.43 to 1.46, respectively, characterizing the 3,6,9-triazatricyclotetradecane derivative as a poorly flowing substance. Conclusion. The experimental data obtained provide the foundation for further pharmaceutical development of the composition and technology for producing drugs based on the 3,6,9-triazatricyclotetradecane derivative.

The article examines patent activity in the field of psychiatry in Russia in 2009—2023. The study was based on 469 invention patents selected from a larger set of medical patents. The analysis covered annual patent dynamics, distribution by ICD-10 diagnostic groups, types of inventions, right holders, and their geographic affiliation. The results show that most patents are related to treatment, diagnosis, and prognosis. Russian right holders predominate in the dataset, while the main centers of patent activity are Moscow, Tomsk, and St. Petersburg. At the time of analysis, 46.9% of patents remained in force. The findings make it possible to describe the structure of the patent landscape in psychiatry and may be useful for research planning and intellectual property management.

The article considers the digitization of the healthcare system as a factor in the transformation of human resource development mechanisms. It is proved that the digital transformation of healthcare is changing not only the technological infrastructure of the industry, but also the requirements for the training, distribution, use and continuous development of medical personnel. It is shown that the introduction of digital solutions, artificial intelligence, telemedicine, data analytics and platform services requires a revision of competence models, educational programs, retraining mechanisms and personnel policy in healthcare. It is concluded that the development of human resources in the context of digitization should be based on a systematic combination of technological modernization, institutional changes and strengthening the digital competencies of medical professionals.

The issues of developing a medical organization management system in the context of digitalization of the healthcare system of the Moscow Region (MO) have been studied. The methodology of improving the medical information system (MIS) and expanding the use of digital solutions has been analyzed, which helps to optimize work processes and, together with changes in the infrastructure of medical organizations, to expand the capabilities of medical professionals and increase the availability of medical care in accordance with the needs of patients. The article shows the possibilities of using digital technologies to introduce technological and organizational innovations into the activities of medical organizations.

The article discusses the problems of professional thinking of pharmaceutical workers. The analysis of sources considering the definition and approaches to the analysis of professional thinking in various fields is presented. The problem of the lack of research and a unified approach to the formation of professional thinking of a pharmaceutical worker is noted.

This article outlines the landscape of an emerging academic field and enables readers to trace the genesis of Pharmaceutical Humanities. The article problematizes the model of the competent or rational consumer (health-literate patient, informed consumer, activated patient, responsible self-medicator), which is central to the constitution of this discipline. In this first communication, the authors analyze the impulses toward autonomization, key conceptual challenges, and analytical practices characteristic of pharmaceutical humanities.