No 4 (2019)

Full Issue

PDF(Russian)
Articles
SOGLAShENIE O LOKALIZATsII V ROSSII PROIZVODSTVA TEST-SISTEMY DLYa DIAGNOSTIKI TUBERKULEZA
- -.
Abstract
Российская компания «Генериум» заключила с компаниями «Оксфорд Иммунотек» и «ФармЛайн» соглашение о локализации производства лабораторного IGRA-теста T-SPOT.TB, используемого для диагностики туберкулеза. T-SPOT.TB был одобрен к применению в России в 2013 г. Его производство будет организовано на мощностях российского фармпроизводителя во Владимирской области. Ожидается, что это позволит снизить стоимость продукта и сделать его более доступным для российских медучреждений. Кроме того, компания «Генериум» будет сотрудничать с компанией «ФармЛайн» в области маркетинга и распространения теста для диагностики туберкулеза. T-SPOT.TB представляет собой набор для экспресс-анализа крови на наличие туберкулезной инфекции, также известного как анализ секреции гамма-интерферона (IGRA). При выполнении теста T-SPOT.TB не наблюдается положительная реакция, вызванная вакциной БЦЖ. Кроме того, на его результаты не влияет статус иммунодефицита. IGRA-тесты, такие как T-SPOT.TB, включены в Перечень основных диагностических тестов in vitro Всемирной организации здравоохранения.
REMEDIUM. 2019;(4):4
views
PRESCRIPTION DRUG INSURANCE: CHOOSING A PATH
Popovich L.D.
Abstract
The patients suffering from serious diseases, the state and society as a whole throw the issue of drug affordability into sharp relief. Officials of regulatory bodies, public health organizers, economists, physicians, specialists and drug circulation experts offer different ways to solve the issue. One of them is to introduce a partial or full reimbursement system of charges for drugs when they are purchased in a pharmacy. This system is also notionally named as the “drug insurance” system aimed at providing the citizens with an opportunity to receive drugs free of charge or with a significant discount during outpatient treatment, which would guarantee them adequate and effective treatment.
REMEDIUM. 2019;(4):6-16
views
Rossiyskie vaktsiny otsenili mezhdunarodnye eksperty
ShIROKOVA I.
Abstract
В 2018 г. российская компания «Петровакс» вывела на рынок первую отечественную четырехваленную вакцину против гриппа. Новые результаты ее исследования, как и других адъювантных вакцин группы Гриппол®, были представлены широкой научной общественности на международной конференции «Influenza vaccines for the world», проходившей в Эдинбурге 2-4 апреля 2019 г., и вызвали живой интерес ее участников.
REMEDIUM. 2019;(4):18-20
views
ANALYSIS OF PATENT PORTFOLIOS IN THE ANTI-INFLUENZA DRUG SEGMENT
Vyukhin M., Rodnin A., Shulgin V.
Abstract
According to statistics, 15% of the world’s population (of which the Russians account for 5-7%) is affected by seasonal influenza viruses during the cold season annually. The high prevalence of this disease, and the social significance of its prevention, determine the high priority of therapeutic areas aimed at combating influenza, which is characteristic of the global pharmaceutical industry in general. Experts of the Patent Family Group analytical centre studied the patent portfolios of the main players in the pharmaceutical market engaged in these areas to identify and evaluate, which areas in terms of the development and distribution of new medicinal products (drugs) dominate today in the Russian Federation.
REMEDIUM. 2019;(4):20-23
views
Mariya DAVYDOVSKAYa: «Sovremennaya farmakoterapiya rasseyannogo skleroza v bol'shinstve sluchaev daet vozmozhnost' zamedlit' progressirovanie zabolevaniya i sokhranit' sposobnost' patsienta k aktivnomu obrazu zhizni»
- -.
Abstract
Многообразие клинических форм и индивидуальное течение заболевания ставят терапию рассеянного склероза (РС) в ряд самых сложных задач практической неврологии. О том, как эта проблема сегодня решается в России и какие новые возможности появляются у пациентов, мы решили узнать у Марии ДАВЫДОВСКОЙ, заместителя директора по научной работе ГБУ «Научно-практический центр клинических исследований и оценки медицинских технологий Департамента здравоохранения города Москвы», д.м.н., профессора кафедры неврологии, нейрохирургии и медицинской генетики ФГБОУ ВО «РНИМУ им. Н.И. Пирогова» МЗ РФ.
REMEDIUM. 2019;(4):24-26
views
PHARMACY MARKET OF BLOOD PRESSURE MONITORS: KEY TRENDS
PROZHERINA J.
Abstract
Arterial hypertension is the most common non-infectious disease in the world [1]. According to the foreign studies, about 35-40% of the adult population suffer from arterial hypertension, and the prevalence of it increases with ageing, accounting for 50-65% in people over 65 years old [2]. In Russia, at least 40% of the population are diagnosed hypertensive [2, 3]. At the same time, hypertension may also be diagnosed in childhood, accounting for about 3.5% of children and adolescents in Russia [3]. Continuous blood pressure monitoring using home-use blood pressure monitors, which are presented in this review by key market trends, is one of the most important measures for the prevention of complications of hypertension.
REMEDIUM. 2019;(4):28-31
views
A STUDY OF FACTORS INFLUENCING PHARMACEUTICAL COUNSELING IN VIETNAMESE COMMUNITY PHARMACIES
Dorofeeva V.V., Tran V.D.
Abstract
A better understanding of pharmacists' viewpoints on pharmaceutical consultation can significantly contribute to improving the quality of pharmaceutical care for patients. The aim of the study was to explore factors influencing patient counseling in pharmacies in Vietnam. Pharmacists working at pharmacies in the four largest cities in Vietnam were randomly selected to participate in this study. The results of the study show that pharmacy staff spend most of their working time on patient consultation. Consultation length is usually from 5 to 10 minutes. Domestic medicines (64,5%), and generic medicines (45,0%) are preferred by pharmacists to choose for patient. Lack of time (43,6%), and knowledge (31,3%) are main barriers to the implementation of high-quality pharmaceutical consultation for patients. The findings of the present study provide an opportunity to improve the quality of pharmaceutical counseling in pharmacies in Vietnam.
REMEDIUM. 2019;(4):32-35
views
MODERN ADVANCED ARTIFICIAL INTELLIGENCE FOR SMART MEDICINE
Kolesnichenko O.Y., Martynov A.V., Pulit V.V., Kolesnichenko Y.Y., Shakirov V.V., Mazelis L.S., Varlamov O.O., Minushkina L.O., Sotnik A.Y., Zhilina T.N., Dorofeev V.P., Smorodin G.N., Zhaparov M.K.
Abstract
Artificial Intelligence is no longer just the topic of discussion. Today this technology is mostly based on Artificial Neural Networks. Pavlov Principle formulated by W.L. Dunin-Barkowski is used for their training. Mathematics compared Pavlov's doctrine with Deep Reinforcement Learning. AI technologies are divided into Computer Vision, images recognition and generation; Speech Recognition and Synthesis; Natural Language Processing; Graph Logic AI, MIVAR logic technology. All of this separately is Narrow AI. Artificial General Intelligence, equal to human, hasn’t been created yet. AGI should include all mentioned technologies. Given social and linguistic nature of the intelligence emergence, developers are paying attention to NLP algorithms and multi-agent environment. Simultaneously with the development of neural networks, adversary attacks emerged, which using the same learning mechanism force a trained neural network to make mistakes. This fact calls in question the future of neural networks in medicine. Big Data and data sets are the environment for AI. European experts have already begun to regulate Big Data for safe Health Care and drugs creation. Despite the difficulties and lack of clear rules, AI is actively being introduced into the private medicine. Due to AI the three new business models have already been created.
REMEDIUM. 2019;(4):36-43
views
Non-adherence as the reason for unreliable result s of a clinical study
MELIKHOV O.G., TATARENKO A.O.
Abstract
The article describes sources of drug non-compliance in clinical trials and methods of assessment of compliance. Protocol violations in terms on non-adherence to study treatment and their effect on study results and on costs of drug development are discussed. Sample size calculation considering possible non-compliance and protocol deviations presented.
REMEDIUM. 2019;(4):44-50
views
CHALLENGES AND ISSUES IN OPERATING PERSONNEL MANAGEMENT DURING THE IMPLEMENTATION OF PHARMACEUTICAL QUALITY SYSTEM
SMIRNOV V.A., GORYACHKIN V.V., SHESTAKOV V.N., ABRAMOVICH R.A.
Abstract
The article attempts to identify the problems in operating personnel management during the implementation of the pharmaceutical quality system (hereinafter the PQS). The problem identification activities included a survey of key personnel of the EAEU pharmaceutical manufacturers, interviews with experts, and practical experience in conducting GMP inspectorate. It was stated that personnel management remains one of the weak points in the implementation of PQS. The personnel provides low support for PQS and shows low interest in ensuring total quality management. Issues of operating personnel management in the implementation of PQS are not reflected in the personnel policies, and many enterprises have not approved any guidelines in this area. The situation is aggravated by shortages of personnel in the industry, contradictory regulatory requirements for training and staff qualifications, as well as lack of availability of educational programs. The authors came to the conclusion that a system of measures for optimizing management procedures and practices should be implemented in all key aspects of the operating personnel management during the implementation of PQS, and the existing system of operating personnel management during the implementation of PQS in EAEU pharmaceutical manufacturers can be considered nothing but satisfactory. The materials can be used to further develop recommendations for improving the operating personnel management in the implementation of PQS.
REMEDIUM. 2019;(4):51-55
views
MONTHLY REVIEW: PRODUCTION, INVESTMENT, FINANCE
Romanova S.
Abstract
Performance analysis of industry enterprises is conducted using the national statistics reports: Form No. P-1, term (monthly), Form No. P-2 Information on Investments in Non-Financial Assets (quarterly), Form No. P-3 Information on Company Financial Status (monthly).
REMEDIUM. 2019;(4):58-65
views
MONTHLY REVIEW: BUSINESS ACTIVITY OF INDUSTRY ENTERPRISES
Romanova S.
Abstract
The rating was carried out using the national accounting statements of top 150 industry enterprises.
REMEDIUM. 2019;(4):66-72
views
TOP-POZITsII. POKAZATELI VEDUShchIKh MIROVYKh I OTEChESTVENNYKh PROIZVODITELEY I DISTRIB'YuTEROV
- -.
Abstract
Производство медицинской продукции Импорт ГЛС в Россию по итогам ноября 2018 года Экспорт ГЛС из России по итогам ноября 2018 года Фармацевтическая реклама ЛП и БАД в российских СМИ в феврале 2018 года
REMEDIUM. 2019;(4):74-79
views

Mailing Address

Address: 105064, Moscow, st. Vorontsovo Pole, 12, building 1

Email: redactor@remedium-journal.ru

Phone: +7(495) 917-48-86



Principal Contact

Sherstneva Elena Vladimirovna
EXECUTIVE SECRETARY
National research Institute of public health named after N. A. Semashko

105064, Vorontsovo Pole st., 12, Moscow


Email: redactor@remedium-journal.ru

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies