Quality of life is one of the most significant indicators of the effectiveness of care for patients with multiple sclerosis. The aim of this work was to summarize the available literature on the characteristics of the main questionnaires used to assess QOL in patients with multiple sclerosis. Materials and methods. The search for relevant literary sources was conducted in the PubMed bibliographic database. The search queries used the keywords: «multiple sclerosis», «questionnaires», «quality of life», and the English-language names of the tests. Publications were selected by title and abstract content. Results. The scientific literature encompasses a wide range of questionnaires for assessing the condition and quality of life of patients with MS. The work considers the main tests. Some of them include a standard block of general questions, for example, SF-36, allowing for comparison between patients with various diseases and healthy subjects. It is noted that the design of questionnaires with the inclusion of general and specialized blocks is very convenient for simultaneously obtaining diverse, comprehensive assessments of the course of MS. In practice, the choice of a specific questionnaire depends on the goals and objectives of its use. Discussion. Some questionnaires are more often used in clinical and epidemiological studies, while others have already been introduced into everyday clinical practice. Before introducing new questionnaires written in foreign languages into the Russian healthcare system, they need to be adapted. Validation of questionnaires in regional healthcare will open up new prospects for their use in regular clinical practice.

questionnaires, quality of life, multiple sclerosis, patient-reported outcomes, review.