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Medical, social aspects of chronic kidney disease
- Authors: Bezymyannyy A.S.1,2, Mingazova E.N.3,2
- Affiliations:
- Directorate for the coordination of the activities of medical organizations of the Moscow Department of Health, Moscow, Russia
- Kazan State Medical University, Kazan, Russia
- N. A. Semashko National Research Institute of Public Health, Moscow, Russian Federation
- Issue: No 1 (2025)
- Pages: 37-41
- Section: Articles
- URL: https://remedium-journal.ru/journal/article/view/1752
- DOI: https://doi.org/10.32687/1561-5936-2025-29-1-37-41
- Cite item
Abstract
In the modern world, there are high risks of kidney damage in the aging population, especially in the presence of severe concomitant conditions such as diabetes mellitus, hypertension, cardiovascular diseases, as well as after complex surgical operations. After reaching the age of 40—50 years, there is a gradual decrease in glomerular filtration rate (GFR), an indicator reflecting the effectiveness of the kidneys. The social determinants of CKD include lifestyle and living conditions, including housing conditions, food security, psychological factors, socio-economic level, educational level, and access to medical care. Screening, primarily aimed at high-risk individuals, including patients with hypertension, diabetes mellitus, and people over the age of 65, is being implemented worldwide to identify people with CKD.
About the authors
Alexey S. Bezymyannyy
Directorate for the coordination of the activities of medical organizations of the Moscow Department of Health, Moscow, Russia; Kazan State Medical University, Kazan, Russia
Email: dkd@zdrav.mos.ru
Elmira N. Mingazova
N. A. Semashko National Research Institute of Public Health, Moscow, Russian Federation; Kazan State Medical University, Kazan, Russia
Email: elmira_mingazova@mail.ru
References
- Wolf U, Ghadir H, Drewas L, Neef R. Underdiagnosed CKD in geriatric trauma patients and potent prevention of renal impairment from polypharmacy risks through Individual Pharmacotherapy Management (IPM-III). J Clin Med. 2023;12(13):4545. doi: 10.3390/jcm12134545
- Vaidya SR, Aeddula NR. Chronic kidney disease. Treasure Island; 2024.
- Oude Engberink A, Tessier G, Kamil I, et al. General practitioners' representation of early-stage CKD is a barrier to adequate management and patient empowerment: a phenomenological study. J Nephrol. 2024;37(2):379—390. doi: 10.1007/s40620-023-01838-y
- Covic A, Säemann M, Filipov J, et al. The importance of early diagnosis and intervention in chronic kidney disease: calls-to-action from nephrologists based mainly in Central/Eastern Europe. Kidney Blood Press. Res. 2024;49(1):218—227. doi: 10.1159/000538165
- Czupryniak L, Mosenzon O, Rychlík I, et al. Barriers to early diagnosis of chronic kidney disease and use of sodium-glucose cotransporter-2 inhibitors for renal protection: a comprehensive review and call to action. Diabetes Obes Metab. 2024;26(10):4165—4177. doi: 10.1111/dom.15789
- Hahn KM, Strutz F. The early diagnosis and treatment of chronic renal insufficiency. Dtsch Arztebl Int. 2024;121(13):428—435. doi: 10.3238/arztebl.m2024.0072
- Stolpe S, Kowall B, Scholz C, et al. High unawareness of chronic kidney disease in Germany. Int J Environ Res Public Health. 2021;18(22):11752. doi: 10.3390/ijerph182211752
- Kim V, Zhakhina G, Gusmanov A, et al. Late diagnosis of CKD and associated survival after initiation of renal replacement therapy in Kazakhstan: analysis of nationwide electronic healthcare registry 2014—2019. Ren Fail. 2024;46(2):2398182. doi: 10.1080/0886022X.2024.2398182
- Matsuoka T, Abe M, Kobayashi H. Iron metabolism and inflammatory mediators in patients with renal dysfunction. Int J Mol Sci. 2024;25(7):3745. doi: 10.3390/ijms25073745
- Koyama AK, Nee R, Yu W, et al. Homelessness and risk of end-stage kidney disease and death in veterans with chronic kidney disease. JAMA Netw Open. 2024;7(9):e2431973. doi: 10.1001/jamanetworkopen.2024.31973
- Ozieh MN, Garacci E, Walker RJ, et al. The cumulative impact of social determinants of health factors on mortality in adults with diabetes and chronic kidney disease. BMC Nephrol. 2021;22(1):76. doi: 10.1186/s12882-021-02277-2
- Quiñones J, Hammad Z. Social determinants of health and chronic kidney disease. Cureus. 2020;12(9):e10266. doi: 10.7759/cureus.10266
- Norris KC, Beech BM. Social determinants of kidney health: focus on poverty. Clin J Am Soc Nephrol. 2021;16(5):809—811. doi: 10.2215/CJN.12710820
- Martino FK, Fanton G, Zanetti F, et al. Stage 5 chronic kidney disease: epidemiological analysis in a NorthEastern district of Italy focusing on access to nephrological care. J Clin Med. 2024;13(4):1144. doi: 10.3390/jcm13041144
- Oliva-Damaso N, Delanaye P, Oliva-Damaso E, et al. Risk-based versus GFR threshold criteria for nephrology referral in chronic kidney disease. Clin Kidney J. 2022;15(11):1996—2005. doi: 10.1093/ckj/sfac104
- Mutatiri C, Ratsch A, McGrail M, et al. Primary and specialist care interaction and referral patterns for individuals with chronic kidney disease: a narrative review. BMC Nephrol. 2024;25(1):149. doi: 10.1186/s12882-024-03585-z
- Hsiao PJ, Wang RL, Hu FK, et al. Biomedical evaluation of early chronic kidney disease in the air force: building a predictive model from the Taiwan Military Health Service. Bioengineering (Basel). 2024;11(3):231. doi: 10.3390/bioengineering11030231
- Sun R, Jia J, Wang S, et al. Mediation effect of antithrombin III between chronic renal insufficiency and chronic coronary artery disease in T2DM patients. Endocrine. 2024;84(3):924—933. doi: 10.1007/s12020-023-03669-04
- Zhang Z, Lv L, Guan S, et al. Association between serum methylmalonic acid and chronic kidney disease in adults: a cross-sectional study from NHANES 2013—2014. Front Endocrinol (Lausanne). 2024;15:1434299. doi: 10.3389/fendo.2024.1434299
- Li K, Pirabhahar S, Thomsett M, et al. Use of kidney failure risk equation as a tool to evaluate referrals from primary care to specialist nephrology care. Intern Med J. 2024;54(7):1126—1135. doi: 10.1111/imj.16377
- Chu C. D., McCulloch C. E., Hsu R. K. et al. Utility of the kidney failure risk equation and estimated GFR for estimating time to kidney failure in advanced CKD. Am J Kidney Dis. 2023;82(4):386—394.e1. doi: 10.1053/j.ajkd.2023.03.014
- Bundy JD, Mills KT, Anderson AH, et al. Prediction of end-stage kidney disease using estimated glomerular filtration rate with and without race: a prospective cohort study. Ann Intern Med. 2022;175(3):305—313. doi: 10.7326/M21-2928
- Patel DM, Churilla BM, Thiessen-Philbrook H, et al. Implementation of the kidney failure risk equation in a United States nephrology clinic. Kidney Int Rep. 2023;8(12):2665—2676. doi: 10.1016/j.ekir.2023.09.001
- Yoon Y, Kim YM, Lee S, et al. Association between neck circumference and chronic kidney disease in Korean adults in the 2019—2021 Korea national health and nutrition examination survey. Nutrients. 2023;15(24):5039. doi: 10.3390/nu15245039
- Kim YJ, Hwang SD, Oh TJ, et al. Association between obesity and chronic kidney disease, defined by both glomerular filtration rate and albuminuria, in Korean adults. Metab Syndr Relat Disord. 2017;15(8):416—422. doi: 10.1089/met.2017.0053
- Hewapathiranage S, Medagedara A, Nanayakkara N. A critical evaluation of anthropological, biological and geo-environmental factors on chronic kidney disease of unknown aetiology in affected area against unaffected area. Nephrology Dialysis Transplantation. 2022;37:284—340. doi: 10.1093/ndt/gfac070.002
- Gillespie N, Mohandas R. New eGFR equations: implications for cardiologists and racial inequities. Am Heart J Plus. 2023;27:100269. doi: 10.1016/j.ahjo.2023.100269
