Email this article 
The pharmaceutical environmental pollution problem: a literature review
- Authors: Makhmudova O.A.1, Khaziakhmetova V.N.1
- Affiliations:
- Kazan (Volga Region) Federal University, Kazan, Russia
- Issue: No 1 (2023)
- Pages: 76-80
- Section: Articles
- URL: https://remedium-journal.ru/journal/article/view/1583
- DOI: https://doi.org/10.32687/1561-5936-2023-27-1-76-80
- Cite item
Abstract
The volume of the pharmaceutical market is increasing every year all over the world, along with this, the amount of pharmaceutical waste is also increasing. Its accumulation in the environment is a global concern. To date, various studies are being carried out to assess the content of medicines in the environment, the potential risk from medicine contamination. This review article conducted a literature review of databases on the topic of proper disposal of medicines and idebtified measures to minimize drug contamination of the environment.
About the authors
Odina A. Makhmudova
Kazan (Volga Region) Federal University, Kazan, Russia
Email: odina_24@mail.ru, https://orcid.org/0000-0002-5215-6539
Veronika N. Khaziakhmetova
Kazan (Volga Region) Federal University, Kazan, Russia
Email: 002
References
- Peña G., Israel O. Pharmaceuticals market, consumption trends and disease incidence are not driving the pharmaceutical research on water and wastewater. Int. J. Environ. Res. Public Health. 2021; 18(5): 2532. doi: 10.3390/ijerph18052532; 2. Alnahas F., Yeboah P., Fliedel L. et al. Expired medication: societal, regulatory and ethical aspects of a wasted opportunity. Int. J. Environ. Res. Public Health. 2020; 17(3): 787. doi: 10.3390/ijerph17030787; 3. Ovod A. I. Features of the Russian pharmaceutical market. Azimuth of scientific research: economics and management. 2021; 10(1): 237—239. (In Russ.); 4. Kelly F., McMillan S., Spinks J. et al. You don't throw these things out: an exploration of medicines retention and disposal practices in Australian homes. BMC Public Health. 2018; 18(1): 1026. doi: 10.1186/s12889-018-5753-6; 5. Barnett-Itzhaki Z., Berman T., Grotto I., Schwartzberg E. Household medical waste disposal policy in Israel. Isr. J. Health Policy Res. 2016; 5: 48. doi: 10.1186/s13584-016-0108-1; 6. Wilkinson J. L., Boxall A. B.A., Kolpin D. W. et al. Pharmaceutical pollution of the world's rivers. Proc. Natl. Acad. Sci. USA. 2022; 119(8): e2113947119. doi: 10.1073/pnas.2113947119; 7. Khan U., Nicell J. Human health relevance of pharmaceutically active compounds in drinking water. AAPS J. 2015; 17(3): 558—585. doi: 10.1208/s12248-015-9729-5; 8. Kumari M., Kumar A. Can pharmaceutical drugs used to treat COVID-19 infection leads to human health risk? A hypothetical study to identify potential risk. Sci. Total Environ. 2021; 778: 146303. doi: 10.1016/j.scitotenv.2021.146303; 9. Barenboym M., Chiganova M. A., Berezovskaya I. V. Peculiarities of pollution of surface water bodies by the components of medicines. Water Industry in Russia. 2014; (3): 131—141. (In Russ.); 10. Franco A., Price O. R., Marshall S. et al. Toward refined environmental scenarios for ecological risk assessment of down-the-drain chemicals in freshwater environments. Integr. Environ. Assess. Manag. 2017; 13(2): 233—248. doi: 10.1002/ieam.1801; 11. Laurenson J. P., Bloom R. A., Page S., Sadrieh N. Ethinyl estradiol and other human pharmaceutical estrogens in the aquatic environment: a review of recent risk assessment data. AAPS J. 2014; 16(2): 299—310. doi: 10.1208/s12248-014-9561-3; 12. Lübbert C., Baars C., Dayakar A. et al. Environmental pollution with antimicrobial agents from bulk drug manufacturing industries in Hyderabad, South India, is associated with dissemination of extended-spectrum beta-lactamase and carbapenemase-producing pathogens. Infection. 2017; 45(4): 479—491. doi: 10.1007/s15010-017-1007-2; 13. Todd P. A., Sorkin E. M. Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs. 1988; 35(3): 244—285. doi: 10.2165/00003495-198835030-00004; 14. Davies N. M., Anderson K. E. Clinical pharmacokinetics of diclofenac. Therapeutic insights and pitfalls. Clin. Pharmacokinet. 1997; 33(3): 184—213. doi: 10.2165/00003088-199733030-00003; 15. Parolini M. Toxicity of the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) acetylsalicylic acid, paracetamol, diclofenac, ibuprofen and naproxen towards freshwater invertebrates: a review. Sci. Total Environ. 2020; 740: 140043. doi: 10.1016/j.scitotenv.2020.140043; 16. Wieczerzak M., Kudłak B., Namieśnik J. Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds. Environ. Sci. Pollut. Res. Int. 2018; 25(19): 18717—18727. doi: 10.1007/s11356-018-2049-4; 17. Guler Y., Ford A. T. Anti-depressants make amphipods see the light. Aquat. Toxicol. 2010; 99(3): 397—404. doi: 10.1016/j.aquatox.2010.05.019; 18. Celander M. C. Cocktail effects on biomarker responses in fish. Aquat. Toxicol. 2011; 105(3—4): 72—77. doi: 10.1016/j.aquatox.2011.06.002
