REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot97710.21518/1561-5936-2020-7-8-84-88Original ArticleInhaled surfactant in patients with COVID-19 who took high-flow oxygen therapy: the results of a retrospective analysisAveryanovA. V.noemail@neicon.ruKlypaT. V.noemail@neicon.ruBalionisO. I.noemail@neicon.ruBychininM. V.noemail@neicon.ruChernyakA. V.noemail@neicon.ruTroitskiyA. V.noemail@neicon.ruFederal Scientific and Clinical Center for Specialized Types of Medical Care and Medical TechnologiesResearch Institute for Pulmonology of the Federal Medical Biological Agency071220207-8848818032022Copyright © 2020,2020This article presents a retrospective analysis of clinical, laboratory data, and outcomes in patients with the diagnosis of SARS-CoV-2 infection with severe bilateral pneumonia complicated by acute respiratory distress syndrome.We analyzed the case histories of the patients who received high-flow nasal cannula oxygen therapy at the intensive care unit of the FGBU FNKC FMBA of Russia. 20 patients received standard therapy. 19 patients were additionally prescribed inhaled Surfactant BL 75mg nebulized twice daily for 5 days.This retrospective analysis shows that the administration of an inhaled surfactant before initiating mechanical ventilation can inhibit theprogression of respiratory failure, prevent mechanical ventilation, and improve survival.COVID-19pneumoniaacute respiratory distress syndromehigh-flow nasal cannula oxygen therapysurfactantпневмонияострый респираторный дистресс-синдромвысокопоточная кислородотерапиясурфактант[Алексеев A.M., Яковлев А.А., Швечкова М.В., Сейлиев А.А., Волчков В.А., Розенберг О.А. 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