REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot86010.21518/1561-5936-2021-2-70-76Original ArticleModern principles in the diagnostics and treatment of iron deficiency anemia and iron deficiency in gastroenterological diseases: review of current clinical guidelinesAlekseevaOlga P.-Semashko Nizhny Novgorod Region Clinical Hospital141220212707617032022Copyright © 2021,2021Anemia is the most frequent systemic complication and extraintestinal manifestation of gastrointestinal diseases, which is likely to be a unique example of chronic iron deficiency combined with anemia of chronic disease. In this case, anemia is not just a laboratory marker, but a complication that requires appropriate diagnostic and therapeutic approaches. At the same time, many global clinical guidelines, including gastroenterological ones, do not contain up-to-date scientific information on the most effective drugs with a favourable safety profile – intravenous iron preparations, which can be used both to manage anemia and replenish iron stores. The evidence base on these drugs is growing fast due to qualitative studies as well as systematic reviews and meta-analyses.iron deficiency anemiairon deficiencyinflammatory bowel diseasesintravenous iron preparationsiron carboxymaltosereview of guidelinesжелезодефицитная анемиядефицит железавоспалительные заболевания кишечникавнутривенные препараты железажелеза карбоксимальтозатобзор рекомендаций1.Gasche C. Anemia in IBD: the overlooked villain. Inflamm Bowel Dis. 2000;6:142–150.2.Gisbert J.P., Gomollon F. Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease. Am J Gastroenterol. 2008;103:1299–1307.3.Pizzi L.T., Weston C.M., Goldfarb N.I. et al. 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