REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot209210.32687/1561-5936-2026-30-3-256-261Original ArticlePain therapy: study of the availability of non-narcotic opioidVerlanNadezhda V.nadverlan@mail.ruMorozTatiana L.moroz_tl@mail.ruKochkinaElena O.kochkina.elena@rambler.ruRozhkovaNina Yu.rozhkova2001@mail.ruBarakhovskayaTatiana V.tvbar@bk.ruIrkutsk State Medical Academy of Postgraduate Education, Branch Campus of the Russian Medical Academy of Continuous Professional Education, Irkutsk, RussiaIrkutsk State Medical University, Irkutsk, Russia2809202630325626129092026Copyright © 2026,2026Introduction. Effective algological therapy is a key aspect of the treatment of patients with pain syndromes. Modern approaches involve the active use of a large arsenal of drugs to form personalized treatment regimens. However, there is a serious problem of insufficient anesthesia patients may not receive adequate anesthesia due to the lack of awareness of doctors about the legal aspects of prescribing potent and narcotic drugs. Aim. Collection and structuring of data on prescribing non-narcotic opioid-like opioid analgesics to patients with chronic pain syndrome. Materials and methods. In study with a convenient sample 36 medical histories and outpatient records of patients receiving medical algological care in different types of 5 medical organizations were analyzed. Statistical processing was carried out in the Jupyter Notebook environment in the Python programming language. Non-parametric criteria χ2, Mann–Whitney, Wilcoxon were used to evaluate the effectiveness of drugs. Independent Ethics Committee of Irkutsk State Medical Academy of Postgraduate Education (protocol No. 9 dated 11/24/2023). Results. The following distribution by MKB-10 classes was recorded: II. New formations — 25 (69.5%); XIII. Musculoskeletal diseases — 8 (22.2%); XIX. Musculoskeletal injuries — 3 (8.3%). In order to correctly compare the efficacy of drugs between two independent groups of patients, the balance was checked by signs (gender, age, type of disease). χ2 criteria for binary and Mann–Whitney for numerical data were used. No statistically significant differences were found, the groups were comparable. A significantly greater reduction in pain was observed in the tramadol group. The assessment of tolerability of drug exposure was at an acceptable level. Specialists, without distinguishing the difference between the prescription of narcotic and psychotropic drugs and potent drugs subject to quantitative accounting, are often reinsured and prescribed tramadol according to the rules for the use of narcotic drugs. Conclusions. 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