REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot209010.32687/1561-5936-2026-30-3-383-386Original ArticleVasily Konstantinovich Anrep (1852—1927)EgoryshevaIrina V.egorysheva@rambler.ruN. A. Semashko National Research Institute of Public Health, Moscow, Russia2809202630338338629092026Copyright © 2026,2026The article is dedicated to V. K. Anrep, a Russian physiologist, pharmacologist, forensic physician, and state and political figure. Anrep was the first in the world to identify and experimentally substantiate the local anesthetic properties of cocaine. His scholarly legacy encompasses original scientific research, pedagogical contributions, and extensive public service. He played a key role in the establishment of the St. Petersburg Womens Medical Institute and served as a deputy in the Third State Duma of the Russian Empire, where he advocated for progressive healthcare reforms.Anrepanesthesiologyforensic medicineSt. Petersburg Women's Medical Institutehealthcare reformshistory of physiologycocaine anesthesiaВ. К. Анрепанестезиологиясудебная медицинаСанкт-Петербургский Женский медицинский институтреформы здравоохранения1.Dedulin V. I. Professor V. K. Anrep (1852—1927) — pages of biography. Problems of Social Hygiene, Public Health and History of Medicine. 1998;(4):54—56. (In Russ.)2.Nazarov V. Yu. Professor Vasily Konstantinovich von Anrep. Forensic Medical Expertise. 2016;59(4):65—68. (In Russ.)3.Von Anrep B. Über die physiologische Wirkung des Cocain. Archiv für die gesammte Physiologie des Menschen und der Thiere. 1879;21(1—2):38—77 (In German)4.Stolyarenko P. Yu. Vasily Anrep — a forgotten pioneer of local anesthesia (part 3). Österreichisches Multiscience Journal. 2020;29(1):6—24. (In Russ.)5.Egorysheva I. V. To the 150th anniversary of N. G. Freyberg, an outstanding domestic specialist in medical and sanitary legislation. Health Care of the Russian Federation. 2009;(5):55—56. (In Russ.)6.Egorysheva I. V., Danilishina E. I. Activity of Government commissions on the reorganization of medical and sanitary administration in Russia (late 19th — early 20th centuries). Problems of Social Hygiene, Public Health and History of Medicine. 1999;5:60—62. (In Russ.)