REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot191510.32687/1561-5936-2026-30-2-135-139Original ArticleCurrent changes in the legal regulation of certain issues of pharmaceutical activityKudimovaAlyona S.liolik.aliona@mail.ruPerederiyEvgeny A.tloef@yandex.ruLugansk State Medical University named after St. Luke, Lugansk, Russia04072026213513907072026Copyright © 2026,2026In September 2025, we celebrated the third anniversary of the Lugansk Peoples Republics admission to the Russian Federation. Since September 30, 2022, the pharmacy sector has also been brought into regulatory compliance. The complexity of this process lies not only in the difficulty of adapting to the requirements of Russian Legislation, but also in their changes during the transition period. We conducted a study of changes in Russian legislation in the field of pharmacy that occurred in 2023—2025.regulatory frameworklegislationLuhansk People's Republictransition periodpharmaceutical activityнормативная базазаконодательствоЛуганская Народная Республикапереходный периодфармацевтическая деятельность1.Perederiy S. V., Perederiy E. A., Dark S. A. Extemporal manufacture of medicines in the Lugansk People's Republic. Morphological almanac named after V. G. Koveshnikov. 2022. 20(3):95—99.2.Alekseeva M. V., Petrukhina I. K. Sanitary and hygienic requirements for the operation of pharmacy facilities. Modern problems of pharmacy: а collection of scientific papers of the III Scientific and Practical online conference with international participation dedicated to the 105th anniversary of Samara State Medical University, Samara, November 18—19, 2024. Samara; 2024:67—70.