REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot181110.32687/1561-5936-2025-29-3-236-240Original ArticleThe peculiarities of the consumption structure of oral hypoglycemic drugs in rural areas of the Lugansk People's RepublicChukarinaYulia Vyacheslavovnaolimpiadapofarmatsilgmu@yandex.ruPerederiiEvgenii Alekseevichtloef@yandex.ruLugansk State Medical University named after St. Luke of the Ministry of Health of the Russian Federation, Lugansk15122025323624017102025Copyright © 2025,2025Currently, 86,208 people live in rural areas of the republic, which is 6.2% of the total number of residents in the region. Strategic inventory planning and the formation of a stable supply are an integral part of the work of pharmacy organizations in rural areas due to the special logistics conditions. Materials and methods. Comparative, marketing, pharmacoeconomic, and content analysis were used in the analysis. The study was conducted in rural areas of the republic with a total population of 8,943 people. The materials for the study were data on the sale of medicinal products from the group of oral hypoglycemic drugs for 2022—2024, obtained from pharmacy retail applications (Algorithm — C). Two analysis methods were used to study consumption: ABC analysis with further representation in the form of a Lorentz curve and nDDD methodology. Results. The coefficients of the breadth and depth of the rural market assortment were 0.53 and 0.56, respectively, in comparison with the market of the republic as a whole. Over the three years studied, the majority of medicines in the general range belong to the group of up to 250 rubles (23 out of 40 items, 63%). The undisputed leaders in the number of doses consumed during the study period are metformin, glimepiride and gliclazide (group A), with more than 5,000 doses consumed per year. The structure of the sales leaders in terms of turnover is somewhat different: while maintaining the leadership positions of metformin and glimepiride, dapagliflozin drugs are the third largest in the groups turnover due to the high cost of packaging. The ratio of consumption in physical and monetary terms has shown that consumption groups do not always correspond to each other. Conclusion. The study showed that the local pharmaceutical market in rural areas had a number of key features: low breadth and depth of assortment in comparison with the market of the republic, the vast majority of drugs are monocomponent — 36 out of 40 trend names (90%), the predominance of goods in the low price category (up to 250 rubles). The sales leaders were monocomponent drugs. The structure of consumption leaders in physical and monetary terms had significant differences.diabetes mellitus, oral hypoglycemic drugs, pharmacoeconomic analysisсахарный диабет, пероральные гипогликемические препараты, фармакоэкономический анализ[Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, Stein C, Basit A, Chan JCN, Mbanya JC, Pavkov ME, Ramachandaran A, Wild SH, James S, Herman WH, Zhang P, Bommer C, Kuo S, Boyko EJ, Magliano DJ. IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119. DOI: 10.1016/j.diabres.2021.109119][IFD Diabetes atlas. 10th edition. 2021. Available at: URL: https://diabetesatlas.org/en/][The top 10 causes of death. World Health Organization. 2024. Available at: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death][Dedov I. I., Shestakova M. V., Vikulova O. K., Zheleznyakova A. V., Isakov M. A., Sazonova D. V., Mokrysheva N. G. Diabetes mellitus in the Russian Federation: dynamics of epidemiological indicators according to the Federal Register of Diabetes Mellitus for the period 2010—2022. Saharnyj diabet. 2023;26(2):104—123. DOI: 10.14341/DM13035 (In Russ.).][Sharofova MU, Sagdieva ShS, Yusufi SD. Diabetes mellitus: the modern state of the issue (part 1)]. Vestnik Avitsenny. 2019;21(3):502—12 (In Russ.). DOI: 10.25005/2074-0581-2019-21-3-502-512][Resolution of the Government of the Luhansk People's Republic dated 04/05/2024 No. 72/24 «On approval of the regional program of the Luhansk People's Republic «Fight against diabetes mellitus» for 2023—2025». The official website of the Government of the LPR [Ofic.website]. Available at: URL: https://sovminlnr.ru / (In Russ.).][Antsiferov M. B., Koteshkova O. M., Dukhareva O. V. Modern approaches to the treatment of patients with type 2 diabetes mellitus with non-insulin drugs. Doktor.Ru. 2021;20(2):30—39 (In Russ.). DOI: 10.31550/1727-2378-2021-20-2-30-39][Zanin A. R., Chukarina Yu. V., Perederii E. A. System analysis of consumption of antibacterial drugs using integrated ABC/ nDDD /VEN matrices and Lorentz curve. Molodezhnyj innovacionnyj vestnik. 2024;13(S1):215 (In Russ.).][O.S.Kozhina, O. M.Pihnastyi. O raschete ob'ema bespovtornoj vyborki. XHV Mezhdunarodnaja nauchno-prakticheskaja konferencija MicroCAD—2017 (Informacionnye tehnologii: nauka, tehnika, tehnologija, obrazovanie, zdorov'e): Vestnik NTU «HPI»; 2017 (In Russ.).][Shubina K. A., Shakirova D. H., Marketing analysis of the range of medicines for physiotherapy. Remedium. 2022;26(2):100—103 (In Russ.). DOI: 10.32687/1561-5936-2022-26-2-100-103][ATC/DDD Index 2025. Available at: URL: https://atcddd.fhi.no/atc_ddd_index/][List of DDDs combined products. Available at: URL: https://atcddd.fhi.no/ddd/list_of_ddds_combined_products/]