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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher">РЕМЕДИУМ</journal-id><journal-title-group><journal-title>РЕМЕДИУМ</journal-title></journal-title-group><issn publication-format="print">1561-5936</issn><issn publication-format="electronic">2658-3534</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1679</article-id><article-id pub-id-type="doi">10.32687/1561-5936-2024-28-1-57-64</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Некоторые аспекты истории развития эпидемий и пандемий</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="eastern" xml:lang="ru"><surname>Мотыгуллина</surname><given-names>Лейсан Илгизовна</given-names></name><bio></bio><email>mleisi20@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="eastern" xml:lang="ru"><surname>Тухбатуллина</surname><given-names>Рузалия Габдулхаковна</given-names></name><bio></bio><email>ruzaliya.tukhbatullina@kazangmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Казанский государственный медицинский университет, Казань, Россия</aff><pub-date date-type="epub" iso-8601-date="2024-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2024</year></pub-date><issue>1</issue><fpage>57</fpage><lpage>64</lpage><history><pub-date date-type="received" iso-8601-date="2025-10-15"><day>15</day><month>10</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2024, АО "Шико"</copyright-statement><copyright-year>2024</copyright-year></permissions><abstract>Представлен обзор литературы, который отражает историю развития эпидемий и пандемий с античных времён до наших дней. Отмечены первые исторические упоминания об острых респираторных вирусных инфекциях, проанализированы научные источники, сообщающие о разработке лекарств и вакцин.</abstract><kwd-group xml:lang="en"><kwd>epidemics</kwd><kwd>pandemics</kwd><kwd>acute respiratory viral infections</kwd><kwd>coronavirus infection</kwd><kwd>review</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эпидемии</kwd><kwd>пандемии</kwd><kwd>острые респираторные вирусные инфекции</kwd><kwd>коронавирусная инфекция</kwd><kwd>обзор</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Briko N. I. Theoretical generalizations in epidemiology: from history to the present. Epidemiology and Vaccinal Prevention. 2018;17(5):5—16.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Barbieva E. B. Optimization of pharmaceutical counseling for patients with infectious and inflammatory diseases of the upper respiratory tract and ENT organs. Izvestiya vuzov Kyrgyzstana. 2022;(6):46—51.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Shirokova I., Prozherina Yu. In the battle against viruses. Remedium. 2021;(1):46—49.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Timchenko V. N., Malinovskaya V. V., Barakina E. V. et al. The role of early etiological interpretation of acute respiratory viral infections in the choice of antiviral therapy in children in hospital settings. Pediatriya im. G. N. Speranskogo. 2020;99(1):100—106.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Narkevich I. A., Nemyatykh O. D., Kuldyrkaeva E. V. Pharmacovigilance system: international experience and prospects in Russia. Farmatsiya. 2016;65(7):3—7.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Kupchenko A. N., Ponezheva Zh.B. Modern principles of diagnosis and treatment of acute respiratory viral infections. Arkhiv vnutrenney meditsiny. 2016;6(1):6—12.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Pappas G., Kiriaze I. J., Falagas M. E. Insights into infectious disease in the era of Hippocrates. Int. J. Infect. Dis. 2008;12(4):347—350.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Blokhin A. A. New and recurring cross-border infections in human life. Puti k miru i bezopasnosti. 2020;59(2):9—26.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Simonyan R. Z. The history of medicine: from ancient times to the present. Cheboksary; 2020.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Potter C. W. A history of influenza. J. Appl. Microbiol. 2001;91(4):572—579.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Farkhutdinova L. M. From the history of the study of infectious diseases. Arkhiv vnutrenney meditsiny. 2021;11(6):416—423.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Orlov A. G., Lipin A. N., Kozlov K. L. Treatment of chronic wounds — a look through the centuries. Kubanskiy nauchnyy meditsinskiy zhurnal. 2016;160(5):147—153.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Mamedov M. K., Kadypova A. A. On the 160th anniversary of the discovery of the cholera vibrio. Cholera and its causative agents are advances in research over a century and a half. Biomeditsina. 2014;(1):23—27.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Waring J. I. A history of medicine in South Carolina 1960—1970. Charleston; 1971.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Kholikov I. V. The spread of epidemics, pandemics and mass diseases as a global challenge of our time. Puti k miru i bezopasnosti. 2020;59(2):27—40.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Gwaltney J. M. Viral respiratory infection therapy: historical perspectives and current trials. Am. J. Med. 2002;112(6A):33S—41S.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Skvortsov V. V., Orlov O. V. Flu and SARS. Meditsinskaya sestra. 2016;(7):3—6.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Stanley W. M. The preparation and properties of influenza virus vaccines concentrated and purified by differential centrifugation. J. Exp. Med. 1945;81:193—218.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Davenport F. M. The search for the ideal influenza vaccine. Postgraduate Med. J. 1979;55:78—86.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Francis T. Vaccination against influenza. Bull. World Health Org. 1953;8:725—741.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Parodi V., de Florentiis D., Martini M., Ansaldi F. Inactivated influenza vaccines: recent progress and implications for the elderly. Drugs Aging. 2011;28:93—106.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Barberis I., Martini M., Iavarone F., Orsi A. Available influenza vaccines: immunization strategies, history and new tools for fighting the disease. J. Prevent. Med. Hyg. 2016; 57:E41—E46.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Francis T., Salk J. E., Pearson H. E., Brown P. N. Protective effect of vaccination against induced influenza A. J. Clin. Invest. 1945;24:536—546.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Weir J. P., Gruber M. F. An overview of the regulation of influenza vaccines in the United States. Influenza Other Respir. Viruses. 2016;10:354—360.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Keitel W. A., Neuzil K. M., Treanor J. Immunogenicity, efficacy of inactivated/live virus seasonal and pandemic vaccines. In: Webster R. G. (eds) Textbook of Influenza. Wiley-Blackwell; 2013:311—326.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Krammer F., Palese P. Advances in the development of influenza virus vaccines. Nature Rev. Drug Discov. 2015;14:167—182.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Zaman M., Ashraf S., Dreyer N. A., Toovey S. Human infection with avian influenza virus, Pakistan, 2007. Emerg. Infect. Dis. 2011;17:1056—1059.</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Crovari P., Alberti M., Alicino C. History and evolution of influenza vaccines. J. Prevent. Med. Hyg. 2011;52:91—94.</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Shannon I., White C. L., Nayak J. L. Understanding immunity in children vaccinated with live attenuated influenza vaccine, USA. J. Pediatr. Infect. Dis. Soc. 2020:9(Suppl 1):10—14.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Falsey A. R., Treanor J. J., Tornieporth N. et al. Randomized, double-blind controlled phase 3 trial comparing the immunogenicity of high-dose and standard-dose influenza vaccine in adults 65 years of age and older. J. Infect. Dis. 2009;200:172—180.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Tisa V., Barberis I., Faccio V. et al. Quadrivalent influenza vaccine: a new opportunity to re-duce the in-fluenza burden. J. Prevent. Med. Hyg. 2016;57:28—33.</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Wille M., Holmes E. C. The ecology and evolution of influenza viruses. Cold Spring Harbor Persp. Med. 2020;10:a038489.</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Lyons, D.M.; Lauring, A. S. Mutation and epistasis in influenza virus evolution. Viruses. 2018;10:407.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Jiang D., Wang Q., Bai Z. et al. Could environment affect the mutation of h1n1 influenza virus? Int. J. Environ. Res. Public Health. 2020;17:3092.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Yen H. L. Current and novel antiviral strategies for influenza infection. Curr. Opin. Virol. 2016;18:126—134.</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Bassetti M., Castaldo N., Carnelutti A. Neuraminidase inhibitors as a strategy for influenza treatment: pros, cons and future perspectives. Exp. Opin. Pharmacother.2019;20(14):1711—1718.</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Tarbet E. B., Hamilton S., Vollmer A. H. et al. A zanamivir dimer with prophylactic and enhanced therapeutic activity against influenza viruses. J. Antimicrob. Chemother. 2014;69(8):2164—2174.</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Vorobjev Y. N. An effective molecular blocker of ion channel of M2 protein as anti-influenza a drug. J. Biomolec. Struct. Dynamics. 2021;39(7):2352—2363.</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Katunina E. A. Amantadine in the treatment of Parkinson’s disease. New opportunities in the context of COVID-19. Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova. 2021;121(4):101—106.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Marra F., Marra C. A., Stiver H. G. A case for rimantadine to be marketed in Canada for prophylaxis of influenza A virus infection. Canad. Respir. J. 2003;10(7):381—388.</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Renzette N., Caffrey D. R., Zeldovich K. B. et al. Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro. J. Virol. 2014;88(1):272—281.</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Boianelli A., Sharma-Chawla N., Bruder D., Hernandez-Vargas E. A. Oseltamivir PK/PD modeling and simulation to evaluate treatment strategies against influenza-pneumococcus coinfection. Front. Cell. Infect. Microbiol. 2016;14(6):60.</mixed-citation></ref><ref id="B43"><label>43.</label><mixed-citation>Takahashi E., Sawabuchi T., Kimoto T. et al. Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 feeding enhances humoral immune responses, which are suppressed by the antiviral neuraminidase inhibitor oseltamivir in influenza A virus-infected mice. J. Dairy Sci. 2019;102(11):9559—9569.</mixed-citation></ref><ref id="B44"><label>44.</label><mixed-citation>Rossignol J. F. Nitazoxanide: a first-in-class broad-spectrum antiviral agent. Antiviral Res. 2014;110:94—103.</mixed-citation></ref><ref id="B45"><label>45.</label><mixed-citation>Belardo G., Cenciarelli O., La Frazia S. et al. Synergistic effect of nitazoxanide with neuraminidase inhibitors against influenza A viruses in vitro. Antimicrob. Agents Chemother. 2015;59(2):1061—1069.</mixed-citation></ref><ref id="B46"><label>46.</label><mixed-citation>Vanderlinden E., Vrancken B., Van Houdt J. et al. Distinct effects of T-705 (Favipiravir) and Ribavirin on influenza virus replication and viral RNA synthesis. Antimicrob. Agents and Chemother. 2016;60(11):6679—6691.</mixed-citation></ref><ref id="B47"><label>47.</label><mixed-citation>Furuta Y., Komeno T., Nakamura T. Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase. Proc. Jpn Acad. Ser. B Phys. Biol. Sci. 2017;93(7):449—463.</mixed-citation></ref><ref id="B48"><label>48.</label><mixed-citation>Shiraki K., Daikoku T. Favipiravir, an anti-influenza drug against life-threatening RNA virus infections. Pharmacol. Ther. 2020;209:107512.</mixed-citation></ref><ref id="B49"><label>49.</label><mixed-citation>Wang C., Horby P. W., Hayden F. G., Gao G. F. A novel coronavirus outbreak of global health concern. Lancet. 2020;395(10223):470—473.</mixed-citation></ref><ref id="B50"><label>50.</label><mixed-citation>Shchelkanov M. Yu., Popova A. Yu., Dedkov V. G. et al. The history of the study and modern classification of coronaviruses (Nidovirales: Coronaviridae). Infektsiya i immunitet. 2020;10(2):221—246.</mixed-citation></ref><ref id="B51"><label>51.</label><mixed-citation>Almatova A. M., Radzhabova M. D., Kavrakov T. D., Sharipov Z. A. Features of the clinical manifestation of COVID-19 infection in the practice of a family doctor. Goals and ways of sustainable economic development. 2021;197—202.</mixed-citation></ref><ref id="B52"><label>52.</label><mixed-citation>Umakanthan S., Sahu P., Ranade A. V. et al. Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgraduate Med. J. 2020;96(1142):753—758.</mixed-citation></ref><ref id="B53"><label>53.</label><mixed-citation>Sharma A., Ahmad Farouk I., Lal S. K. COVID-19: a review on the novel coronavirus disease evolution, transmission, detection, control and prevention. Viruses. 2021;13(2):202.</mixed-citation></ref><ref id="B54"><label>54.</label><mixed-citation>Romanov B. K. Coronavirus infection COVID-2019. Bezopasnost&amp;apos; i risk farmakoterapii. 2020;8(1):3—8.</mixed-citation></ref></ref-list></back></article>
