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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">REMEDIUM</journal-id><journal-title-group><journal-title>REMEDIUM</journal-title></journal-title-group><issn publication-format="print">1561-5936</issn><issn publication-format="electronic">2658-3534</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1590</article-id><article-id pub-id-type="doi">10.32687/1561-5936-2023-27-1-26-32</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Determination of management tactics for patients with cervical diseases based on the calculation of the prognostic index</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Aminodova</surname><given-names>Isabella P.</given-names></name><bio></bio><email>001</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Vasilev</surname><given-names>Michail D.</given-names></name><bio></bio><email>002</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Makarova</surname><given-names>Ekaterina V.</given-names></name><bio></bio><email>003</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Beneslavskaya</surname><given-names>Olga A.</given-names></name><bio></bio><email>004</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff id="aff-1">The Medical Center «Belaya Roza» Ivanovo, Russian Federation</aff><aff id="aff-2">N. A. Semashko National Research Institute of Public Health, Moscow, Russian Federation</aff><pub-date date-type="epub" iso-8601-date="2023-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2023</year></pub-date><issue>1</issue><fpage>26</fpage><lpage>32</lpage><history><pub-date date-type="received" iso-8601-date="2025-10-09"><day>09</day><month>10</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2023,</copyright-statement><copyright-year>2023</copyright-year></permissions><abstract>Today in cervical cancer diagnostics special attention is paid to the identification of a cohort of women with relatively high risk for the disease development among general population. The objective of the study was development and evaluation of possible prognostic criteria for treatment tactics determination in women with cervical diseases. Based on the data obtained by the method of intensive indicators normalization, a scale for risk prediction of cervical cancer development was formed and its effectiveness was evaluated. Our analysis demonstrated feasibility of introducing into clinical practice a method for cervical cancer developing risk assessment with a four-degree prognostic scale based on a comprehensive examination. This research could contribute to an evidence-based medical decision-making in management of patients with abnormal primary examination results; help in shortening the diagnostic interval for cervical diseases verification of; as such as increase the effectiveness of cervical cancer secondary prevention.</abstract><kwd-group xml:lang="en"><kwd>diseases of the cervix uteri, cervical intraepithelial neoplasia, a comprehensive examination, prognosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>заболевания шейки матки, дисплазия шейки матки комплексное обследование, прогнозирование</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Cervical cancer. Eds. I. V. Berlev, A. F. Urmancheeva. St. Petersburg; 2018. (In Russ.)</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Alexandrova L. M., Gretsova O. P., Petrova G. V. et al. Preventable cervical cancer mortality as indicator of disease prevention effectiveness. The Russian Journal of Preventive Medicine. 2020; 23(3): 56—63. (In Russ.) doi: 10.17116/profmed20202303156</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Malignant neoplasms in Russia in 2018 (morbidity and mortality). Eds. A. D. Kaprin, V. V. Starinsky, G. M. Petrova. Moscow; 2019. (In Russ.)</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Rogovskaya S. I., Shabalova I. P., Ulumbekova G. E. et al. The cervical cancer prevention in Russia. Healthcare Management: News. Views. Education. Bulletin of VSHOUZ. 2021; 7(4): 16—31. (In Russ.) doi: 10.33029/2411-8621-2021-7-4-16-31</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Fattakhov T. A., Mironova A. A., Pyankova A. I., Shahzadova A. O. Cancer mortality in Russia for the period of 1965—2019: main structural changes and trends. Siberian Journal of Oncology. 2021; 20(4): 5—20. (In Russ.) doi: 10.21294/1814-4861-2021-20-4-5-20</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Budaev B. S., Banzarova L. P., Bogdanova O. G., Tarmaeva I. Yu. Analysis of malignant neoplasms mortality rate of the population at the regional level. Pacific Medical Journal. 2021; (3): 71—76. (In Russ.) doi: 10.34215/1609-1175-2021-3-71-76</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Alexandrova L. M., Mamontov A. S., Kaprin A. D. The impact of the COVID-19 pandemic on the diagnosis of malignant neoplasms during preventive medical examinations. P. A. Herzen Journal of Oncology. 2021; 10(6): 77—82. (In Russ.) doi: 10.17116/onkolog20211006177</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Merabishvili V. M. Medium-term prognosis of cancer mortality among the population of Russia. Siberian Journal of Oncology. 2019; 18(4): 5—12. (In Russ.) doi: 10.21294/1814-4861-2019-18-4-5-12</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Bayramova G. R., Fayzullin L. Z., Korolkova A. I. et al. Cervical cancer screening: what is new in global practice? Obstetrics and Gynecology. 2016; (7): 17—21. (In Russ.) doi: 10.18565/aig.2016.7.17—21</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Bebneva T. N. We know how, but we do not use enough. Status Praesens. Gynecology, obstetrics, barren marriage. 2017; (3): 113—120. (In Russ.)</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Belokrinitskaya T. E., Frolova N. I., Tarbaeva D. A. et al. Confounding factors for papillomavirus infection and cervical dysplasia in young women. Doctor.ru. 2015; (14): 6—11. (In Russ.)</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Burmenskaya O. V., Nazarova N. M., Prilepskaya V. N. et al. Prediction of the risk and progression of cervical intraepithelial neoplasias associated with papillomavirus infection. Obstetrics and Gynecology. 2016; (2): 92—98. (In Russ.) doi: 10.18565/aig.2016.2.92—98</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Shmakova N. A., Chistyakova G. N., Kononova I. N. et al. High oncogenic risk of cervical intraepithelial neoplasia and cervical cancer: the urgency of the problem, the search for prospects (literature review). Russian Journal of Human Reproduction. 2021; 27(1): 33—38. (In Russ.) doi: 10.17116/repro20212701133</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Mikhalkina E. V., Skachkova L. S., Kit O. I., Fomenko Yu. A. Socioeconomic predictors of cancer. Journal of Institutional Studies. 2020; 12(3): 122—141. (In Russ.) doi: 10.17835/2076-6297.2020.12.3.122—141</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Khoroshevskaya I. V., Bel&amp;apos;skikh O. L. Risk factors for ovarian cancer. Youth Innovation Bulletin. 2019; 8(2): 159—160. (In Russ.)</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Petrov Yu. A., Blesmanovich A. E., Bagnovskaya A. G. From background processes to cervical cancer: causes, diagnosis and prevention. Chief Physician of the South of Russia. 2020; (4): 36—39. (In Russ.)</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Efimova N. V., Rukavishnikov V. S., Myl’Nikova I. V. Comprehensive epidemiological analysis of the risk of malignant neoplasms: experience of the implementation. Hygiene and Sanitation. 2021; 100(11): 1317—1322. (In Russ.) doi: 10.47470/0016-9900-2021-100-11-1317-1322</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Firichenko S. V., Manukhin I. B., Rogovskaya S. I., Manukhina E. I. Pitfalls in cervical screening. Doctor.ru. 2018; (2): 26—34. (In Russ.)</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Breast medicine and gynecological diseases. Ed. V. E. Radzinsky. Moscow; 2017. (In Russ.)</mixed-citation></ref></ref-list></back></article>
