REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot145610.32687/1561-5936-2022-26-3-255-261Original ArticleDigital transformation of pharmaceutical companies in the conditions of import substitutionKoshechkinK. A.koshechkin_k_a@staff.sechenov.ruIgnatievA. A.-LebedevG. S.-FartushnyE. N.-I. M. Sechenov First Moscow State Medical UniversityLaboratory of Advanced Technologies1512202226325526121092022Copyright © 2022,2022The article describes current approaches to the digital transformation of pharmaceutical companies, taking into account the specifics of the requirements of import substitution of software for domestic production systems. Based on publications and open sources of information, the most relevant solutions were selected for the implementation of ERP systems, business analytics, cloud infrastructure, work with big data, the Internet of Things, for robotic automation of processes based on machine learning and artificial intelligence. These systems are analyzed from the point of view of their applicability in the framework of the digital transformation of pharmaceutical companies. Their brief characteristics are given and the purpose is described. The research of the software market showed the availability of affordable solutions of domestic development that can be implemented at a pharmaceutical enterprise to carry out work within the framework of the digital transformation of business processes.digital transformationimport substitutionERP systembusiness intelligence systemcloud infrastructurebig dataInternet of thingsrobotic process automationцифровая трансформацияимпортозамещениеERP-системасистема бизнес-аналитикиоблачная инфраструктурабольшие данныеинтернет вещейроботизированная автоматизация процессов1.Кошечкин К. А., Яворский А. Н. Цифровая биомедицина и биофармацевтика // Ремедиум. 2018. Т. 1-2. С. 16-20.2.Blackstone E. A., Fuhr J. P.Jr., Pociask S. The health and economic effects of counterfeit drugs // Am. Heal. Drug Benefits. 2014. Vol. 7, N 4. P. 216-224.3.Лебедев Г. С., Фартушный Э. Н., Шадеркин И. А. и др. Создание информационной системы поддержки принятия врачебных решений на основе методов доказательной медицины // Журнал телемедицины и электронного здравоохранения. 2019. Т. 5, № 1. С. 8-16.4.Erokhin A., Koshechkin K., Ryabkov I. The distributed ledger technology as a measure to minimize risks of poor-quality pharmaceuticals circulation // PeerJ Comput. Sci. 2020. Vol. 6. P. e292. DOI: 10.7717/peerj-cs.292