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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">REMEDIUM</journal-id><journal-title-group><journal-title>REMEDIUM</journal-title></journal-title-group><issn publication-format="print">1561-5936</issn><issn publication-format="electronic">2658-3534</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1341</article-id><article-id pub-id-type="doi">10.21518/1561-5936-2018-12-40-42</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>What threatens type 2 diabetes patients' adherence to treatment?</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Kaplya-Bubenets</surname><given-names>Vera</given-names></name><bio></bio><email>noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Remedium</aff><pub-date date-type="epub" iso-8601-date="2018-12-12" publication-format="electronic"><day>12</day><month>12</month><year>2018</year></pub-date><issue>12</issue><fpage>40</fpage><lpage>42</lpage><history><pub-date date-type="received" iso-8601-date="2022-03-18"><day>18</day><month>03</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2018,</copyright-statement><copyright-year>2018</copyright-year></permissions><abstract>About 50% of patients stop taking medication to treat diabetes mellitus on their own within one year after drug prescription. Non-adherence to prescribed therapy is a serious threat to the health of the patient himself, and to the health care system as a whole, as it leads to the progression of the disease, the development of complications, increased frequency of hospitalization and the risk of death. Side effects of therapy and their fear by patients and doctors often became the cause of non-adherence to medical recommendations. The development of new drugs with a more convenient regimen and an improved safety profile is one of the ways to increase adherence to prescribed therapy, improve treatment outcomes and reduce the costs of the health care system.</abstract><kwd-group xml:lang="en"><kwd>type 2 diabetes</kwd><kwd>adherence to therapy</kwd><kwd>pharmacotherapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>сахарный диабет 2-го типа</kwd><kwd>приверженность терапии</kwd><kwd>фармакотерапия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Steven V. Edelman and William H. Polonsky Type 2 Diabetes in the Real World: The Elusive Nature of Glycemic Control. Diabetes Care. 2017 Nov; 40 (11): 1425-1432.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Leah L Zulliget al., Improving diabetes medication adherence: successful, scalable interventions. Patient Prefer Adherence. 2015; 9: 139-149.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Moreira, R. O., Cobas, R. &amp; Lopes Assis Coelho, Combination of basal insulin and GLP-1 receptor agonist: is this the end of basal insulin alone in the treatment of type 2 diabetes? Diabetology &amp; Metabolic Syndrome. 2018; 10: 26.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Дедов И.И., Шестакова М.В., Викулова О.К. Сахарный диабет в Российской Федерации: распространенность, заболеваемость, смертность, параметры углеводного обмена и структура сахароснижающей терапии по данным федерального регистра сахарного диабета, статус 2017 г. Сахарный диабет. 2018; 21 (3): 144-159.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Материалы симпозиума с международным участием «Современная инъекционная терапия сахарного диабета 2 типа: больше возможностей, меньше ограничений». В рамках Санкт-Петербургской ежегодной школы эндокринологов - 2018, 23-25 ноября 2018 года, Санкт-Петербург.</mixed-citation></ref></ref-list></back></article>
