REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot1191Original ArticlePharmacoeconomic analysis of fulvestrant use in the first line therapy of metastatic breast cancerKrysanovI. Snoemail@neicon.ruKonstantinovaM. M.noemail@neicon.ruErmakovaV. Yu.noemail@neicon.ruVaskovaL. B.noemail@neicon.ruTyapkinaM. Vnoemail@neicon.ruResearch Institute of Clinical Economic Expertise and PharmacoeconomicsVladimirsky Moscow Regional Research Clinical InstituteSechenov First Moscow State Medical University011220181-2334018032022Copyright © 2018,2018Breast cancer (BC) is associated with a high mortality rate among women all over the world. In the Russian Federation (RF) in 2015, 66,366 female patients were diagnosed with breast cancer for the first time, which accounted for 20.8% of the total tumour pathology in women. Early detection of breast cancer at B (I and II) stage has increased from 61.8% to 69.5% over the past 10 years, while mortality rate in the first year after diagnosis has decreased from 10.9 to 6% in 2015 over the same period, nevertheless, until now breast cancer remains ranked 1st in the mortality structure of the female population and is 17.0%. The main objective of treatment of patients with metastatic breast cancer (mBC) is the maximum extension and preservation of quality of life.mBCfulvestrant"costs - efficacy"РМЖфулвестрант«затраты - эффективность»1.Клинические рекомендации РООМ по лечению рака молочной железы. Режим доступа: http://breastcancersociety.ru/rek/view/289.2.Клинические рекомендации Российского профессионального общества онкологов-химиотерапевтов (RUSSCO). Рак молочной железы. Режим доступа: http://oncology-association.ru/klinicheskie-recomendatsii).3.Кондратьев В.Б. IV Российская онкологическая конференция. 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