REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot117310.21518/1561-5936-2019-12-21-22Научная статьяIf you can’t breathe through your noseKalininaN.-Remedium1212201912212218032022Copyright © 2019,2019According to figures provided by the Ministry of Health, the autumn-winter period is characterized by the prevalence of outbreaks of ARVI and influenza. In case of ARVI of no influenza etiology, the disease develops gradually, it is most often accompanied by cough, and begins with usual fatigue and rhinitis (runny nose), which makes nasal breathing difficult and worsens the patient’s condition. That is why the treatment of rhinitis is an important component of the comprehensive treatment of ARVI and influenza.vasoconstrictor drugsdecongestantsARVIdomestic sprays ratingсосудосуживающие препаратыдеконгестантыОРВИрейтинг отечественных спреев[Дронов И.А., Малахов А.Б. Возможности повышения эффективности и применения назальных деконгестантов у детей. Эффективная фармакотерапия. Пульмонология и оториноларингология. 2013; (39):4–8. Режим доступа: Dronоv I.A., Malakhov A.B. Opportunities of improving the efficacy and safety of use of nasal decongestants in children. Effective Pharmacotherapy. Pulmonology & Otorhinolaryngology. 2013; (39):4–8.][Petruson B., Hansson H.A. Function and structure of the nasal mucosa after 6 weeks’ use of nose-drops. Acta Otolaryngol. 1982;94 (5–6):563–569. doi: 10.3109/00016488209128948.][Keck T., Leiacker R., Schick M. et al. Temperature and humidity profile of the par sinuses before and after mucosal decongestion by xylometazolin. Laryngorhinootologie 2000;79 (12):749–752. doi: 10.1055/s-2000–9138.][Pradalier A. Pharmacological and clinical evalutation of nasal obstruction: applica xylometazoline. Therapie. 2006;61 (1):3–11. doi: 10.2515/therapie:2006002.]