REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot117310.21518/1561-5936-2019-12-21-22Original ArticleIf you can’t breathe through your noseKalininaN.-Remedium1212201912212218032022Copyright © 2019,2019According to figures  provided by the  Ministry  of Health, the  autumn-winter period is characterized  by the  prevalence  of outbreaks of ARVI and influenza. In case of ARVI of no influenza  etiology,  the disease  develops  gradually, it is most often accompanied by cough, and begins  with usual fatigue and rhinitis  (runny nose), which makes nasal breathing difficult  and worsens  the  patient’s condition.  That is  why the  treatment  of rhinitis  is  an important  component  of the  comprehensive treatment  of ARVI and influenza.vasoconstrictor drugsdecongestantsARVIdomestic sprays ratingсосудосуживающие препаратыдеконгестантыОРВИрейтинг отечественных спреев1.Дронов И.А., Малахов А.Б. Возможности повышения эффективности и применения назальных деконгестантов у детей. Эффективная фармакотерапия. Пульмонология и оториноларингология. 2013; (39):4–8. Режим доступа: Dronоv I.A., Malakhov A.B. Opportunities of improving the efficacy and safety of use of nasal decongestants in children. Effective Pharmacotherapy. Pulmonology & Otorhinolaryngology. 2013; (39):4–8.2.Petruson B., Hansson H.A. Function and structure of the nasal mucosa after 6 weeks’ use of nose-drops. Acta Otolaryngol. 1982;94 (5–6):563–569. doi: 10.3109/00016488209128948.3.Keck T., Leiacker R., Schick M. et al. Temperature and humidity profile of the par sinuses before and after mucosal decongestion by xylometazolin. Laryngorhinootologie 2000;79 (12):749–752. doi: 10.1055/s-2000–9138.4.Pradalier A. Pharmacological and clinical evalutation of nasal obstruction: applica xylometazoline. Therapie. 2006;61 (1):3–11. doi: 10.2515/therapie:2006002.