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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">REMEDIUM</journal-id><journal-title-group><journal-title>REMEDIUM</journal-title></journal-title-group><issn publication-format="print">1561-5936</issn><issn publication-format="electronic">2658-3534</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1084</article-id><article-id pub-id-type="doi">10.21518/1561-5936-2019-5-52-55</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Analysis of compliance with the rules of vacation prescription medicines from pharmacies</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Moroz</surname><given-names>T. L.</given-names></name><bio></bio><email>noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ryzhova</surname><given-names>O. A.</given-names></name><bio></bio><email>noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Irkutsk State Medical Academy of Postgraduate Education</aff><pub-date date-type="epub" iso-8601-date="2019-12-05" publication-format="electronic"><day>05</day><month>12</month><year>2019</year></pub-date><issue>5</issue><fpage>52</fpage><lpage>55</lpage><history><pub-date date-type="received" iso-8601-date="2022-03-18"><day>18</day><month>03</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2019,</copyright-statement><copyright-year>2019</copyright-year></permissions><abstract>The purpose of the study To analyze the causes of violations of the rules of prescription drugs from pharmacy organizations. Research problem. The problem of prescription drugs in the Russian Federation is very acute. The population of the Russian Federation the main part of medicines, except subject to subject-quantitative accounting and received preferential categories of patients, acquires in pharmacies without a doctor's prescription, which leads to total self-treatment of the population, the consequence of which is a decrease in the safety of the use of medicines. This article is devoted to the study of the level of awareness of pharmaceutical specialists on compliance with the requirements of existing regulations for the release of prescription drugs from pharmacies. Methods. The study was conducted by an anonymous survey of 100 pharmaceutical specialists engaged in the sale of medicines from pharmacies in Irkutsk. Results. The most frequent violation is the release of prescription medicines without a doctor's prescription. The survey of specialists showed that only 33% of respondents know the current regulatory document on the issue of medicines, 40% of specialists as a source of information about medicines called the Internet and 40% of respondents do not consider it necessary to release prescription drugs strictly according to prescriptions. 42% of respondents do not know the rules of registration of prescriptions for medicines containing narcotic drugs, psychotropic substances and subject to subject-quantitative accounting. Among the factors that lead to violation of the rules of medicines, 67% of respondents named the dependence of wages on turnover and 57% - high competition between pharmacies. Conclusion The widespread non-compliance with the rules of prescription medicines from pharmacies dramatically reduces the safety of their use by patients, leading to the further spread of self-medication.</abstract><kwd-group xml:lang="en"><kwd>prescription medications</kwd><kwd>the rules of vacation medicines</kwd><kwd>pharmaceutical specialists</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рецептурные лекарственные препараты</kwd><kwd>правила отпуска из аптек</kwd><kwd>фармацевтические специалисты</kwd><kwd>самолечение</kwd><kwd>рецептурные лекарственные препараты</kwd><kwd>правила отпуска из аптек</kwd><kwd>фармацевтические специалисты</kwd><kwd>самолечение</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Рыжова О.А., Мороз Т.Л. Организационные проблемы обеспечения безопасности лекарственных препаратов: монография. 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