REMEDIUMREMEDIUM1561-59362658-3534Joint-Stock Company Chicot1011Original ArticleThe problem of the availability of intra-pharmaceutical drugs(on the example of the Irkutsk region)MorozT. L.noemail@neicon.ruRyzhovaO. A.noemail@neicon.ruIrkutsk State Medical Academy of Postgraduate Education1012202010545718032022Copyright © 2020,2020Introduction. Due to the high demand for custom-made medicines, the aim of this study was to analyze the physical availability of custom-made medicines for the population of the Irkutsk region.Materials and methods. A comparative analysis of the number of production pharmacies in the Irkutsk region in 2000 and 2019 was carried out. The analysis of the problems of opening production pharmacies is carried out.Results. The analysis found that in 2000 in the Irkutsk region there were 166 production pharmacies, and in 2019 only 19 remained, i.e. there was a decrease in the number of municipal production pharmacies by 9 times. According to the regional Ministry of Health, 195.5 thousand people (8.2% of the region’s population) are not able to receive pharmaceutical products manufactured at the pharmacy due to the closure of municipal pharmacies in 8 districts.Conclusion. To resolve the most difficult situation, it is necessary at the state level: to determine the need for drugs for extreme production by assortment and analyze the range of analog industrial production available on the global pharmaceutical market, organize their registration in the Russian Federation and subsequent purchases; to consider the possibility of opening in large cities production according to GMP standards and the production of necessary medicines with a longer shelf life for the needs of organizations and the public and their delivery to consumers.medicinesintra-pharmaceutical manufacturingavailability of medicinesmedicinesлекарственные средствалекарственные препаратывнутриаптечное изготовлениедоступность лекарственных препаратов1.Федеральный закон от апреля 2010 г. «Об обращении лекарственных средств». Режим доступа: http://www.consultant.ru/ document/cons_doc_LAW_99350/.2.Федеральный закон от 6 марта 2019 г. №18-ФЗ «О внесении изменений в Федеральный закон «Об основах охраны здоровья граждан в Российской Федерации» по вопросам оказания паллиативной медицинской помощи». Режим доступа: https:// base.garant.ru/72189464/.3.Приказ Минздрава России от 26.10.2015 №751н «Об утверждении правил изготовления и отпуска лекарственных препаратов для медицинского применения аптечными организациями, индивидуальными предпринимателями, имеющими лицензию на фармацевтическую деятельность». Режим доступа: http://www.consultant.ru/document/ cons_doc_LAW_197197/.