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Methods of comprehensive environmental assessment of pharmaceutical industry facilities
- Authors: Golovin A.V.1, Pyatigorskaya N.V.1,2, Brkich L.L.1,3, Zyryanov O.A.1, Belyaev V.V.1
- Affiliations:
- Sechenov First Moscow State Medical University, 119048, Moscow, Russia
- Pacific State Medical University, 690002, Vladivostok, Russia
- N. A. Semashko National Research Institute of Public Health, Moscow, Russia
- Issue: No 2 (2026)
- Pages: 178-182
- Section: Articles
- URL: https://remedium-journal.ru/journal/article/view/1923
- DOI: https://doi.org/10.32687/1561-5936-2026-30-2-178-182
- Cite item
Abstract
The article examines current approaches to environmental assessment of pharmaceutical enterprises, taking into account the specific nature of emissions of biologically active substances capable of exerting effects at low concentrations. A sequential assessment framework is analyzed: "source ? infrastructure ? wastewater treatment ? receiving ecosystem ? accumulation zones." The need to combine targeted analysis of priority compounds with non-targeted methods, including high-resolution mass spectrometry, is substantiated to ensure comprehensive identification of contaminants. The importance of integrating chemical, biological, and ecotoxicological methods, including the assessment of antimicrobial resistance, is demonstrated. High variability of emissions and the need for long-term monitoring are highlighted. Key principles of a comprehensive, risk-based approach aimed at improving the reliability of environmental impact assessment are formulated.
About the authors
Aleksei V. Golovin
Sechenov First Moscow State Medical University, 119048, Moscow, Russia
Email: avg@vmin.ru
Nathalia V. Pyatigorskaya
Sechenov First Moscow State Medical University, 119048, Moscow, Russia; Pacific State Medical University, 690002, Vladivostok, Russia
Email: pyatigorskaya_n_v@staff.sechenov.ru
Liliana L. Brkich
Sechenov First Moscow State Medical University, 119048, Moscow, Russia; N. A. Semashko National Research Institute of Public Health, Moscow, Russia
Email: brkich.lily@gmail.com
Oleg A. Zyryanov
Sechenov First Moscow State Medical University, 119048, Moscow, Russia
Email: zyryanov_o_a@staff.sechenov.ru
Vasiliy V. Belyaev
Sechenov First Moscow State Medical University, 119048, Moscow, RussiaReferences
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