условия использования материалов

Фармрынок / Pharm market

Роль НПВС в лечении ОА: новые данные / The role of NSAIDs in the treatment of OA: new data

DOI: http://dx.doi.org/10.21518/1561-5936-2020-7-8-29-32

Алексей Водовозов, врач-терапевт высшей категории, «Ремедиум»

Современная терапия остеоартрозов любых локализаций строится по принципу максимально возможного учета интересов пациента, в том числе за счет тщательного выстраивания баланса пользы, подтвержденной в строгом соответствии с принципами доказательной медицины, и потенциального вреда за счет нежелательных побочных эффектов применяемых ЛС. НПВС при этом по праву заняли место препаратов выбора, однако долгое время акцент делался на системном их применении, на пероральных формах. Новые рекомендации Американского колледжа ревматологии (ACR) и Международного общества по изучению остеоартроза (OARSI) смещают центр тяжести в сторону топических формы, ориентируясь на актуальные данные об их эффективности и безопасности. При этом от ряда ранее применявшихся средств, например, хондропротекторов, рекомендовано отказаться.

Alexey Vodovozov, physician of superior expert category, Remedium

Modern therapy for osteoarthritis of any localization follows the principle on integrating patients’ concerns as much as possible, including thorough building of balance of benefits confirmed in strict accordance with the principles of evidence-based medicine, and potential harm due to unwanted side effects of the drugs used. In this case, NSAIDs gained a rightful place of drugs of choice, but the emphasis was placed on their systemic use, on oral forms for a long time. The new guidelines from the American College of Rheumatology (ACR) and the Osteoarthritis Research Society International (OARSI) are shifting the center of balance towards topical forms, focusing on current evidence of their effectiveness and safety. At the same time, it is recommended to refuse some previously used agents, for example, chondroprotectors.

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Ключевые слова: ACR, OARSI, остеоартроз, НПВС, хондропротекторы, клинические рекомендации, вольтарен, топические формы, osteoarthritis, NSAIDs, chondroprotectors, clinical guidelines, voltaren, topical forms

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